Okay, after looking at the options, I think I'm going to go with the "Complement System" in the style of a hollywood military thriller, e.g.
"A tetse fly bite has injected a protozoa into the bloodstream of the victim. Unless it is stopped, it will multiply out of control and cause fatal damage to the host's immune system. Too big to be stopped by white blood cells, the immune system's only hope lies with its smallest members..."
Cue various action movie cliches, not to mention a ticking timer...
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